What
is COVID 19?
The virus is not
an living organism but a protein molecule consisting of DNA covered by a layer
of lipid which can absorbed by all the cells such as nasal, mucosal, ocular and
induces genetic mutation amongst the population.
How
does COVID 19 survive?
The viral genome
of corona virus is fragile and is protected by a layer of fat. The virus has
the tendency to stay on surfaces for atleast 6-9 hours, also called as FOMITES.
These are nothing but contaminated surfaces which cross infect other human
beings. This virus has a pH of 5.5 to
8.5 That is why any soap or detergents is the best remedy to prevent this virus.
By dissolving
the fat layer, the protein molecule disperses and breaks down on its own. Alcohol
or any mixture with alcohol over 65% dissolves the fat, especially the external
lipid layer of the virus. Any mix with 1 part bleach and 5 parts water directly
dissolves the protein, breaks it down from the inside. Oxygenated water helps
long after soap, alcohol and chlorine, because peroxide dissolves the virus
protein, but you have to use it pure and it hurts your skin.
The virus
molecules remain very stable in external cold,or artificial as air conditioners
in houses and cars. Theyalso need moisture to stay stable, and especially darkness.
Therefore, dehumidified, dry, warm and bright environments will degrade it
faster. UV LIGHT on any object that may contain it breaks down the virus
protein.
COVID-19 virus
can persist on inanimate surfaces like metal, glass or plastic for upto 9 days,
but can be efficiently inactivated by surface disinfection procedures with 62–71%
ethanol, 0.5% hydrogen peroxide or 0.1% sodium hypochlorite within 1 minute. Other
biocidal agents such as 0.05–0.2% benzalkonium chloride or 0.02% chlorhexidine
digluconate are less effective.
CLINICAL
FEATURES OF COVID 19
Incubation
period
The exact
incubation period is not known. It is presumed to be between 2 to 14 days after
exposure, with most cases occurring within 5 days after exposure.
The
spectrum of illness severity
Most infections
are self limiting. COVID-19 tends to cause more severe illness in elderlypopulation
or in patients with underlying medical problems.
• Mild illness
was reported in 81% patients
• Severe illness
( Hypoxemia, >50% lung involvement on imaging within 24 to 48
hours) in 14%
• Critical
Disease (Respiratory failure, shock, multi-organ dysfunction syndrome) was
reported in 5
percent
Age
affected
• Mostly middle
aged (>30 years) and elderly.
• Symptomatic
infection in children appears to be uncommon, and when it occurs, it is
usually mild
Common
clinical features at the onset of illness were:
•Fever in 88%
•Fatigue in 38%
•Dry cough in
67%
•Myalgias in
14.9%
•Dyspnea in
18.7%
Pneumonia
appears to be the most common and severe manifestation of infection. In this group
of patients breathing difficulty developed after a median of five days of
illness. Acute respiratory distress syndrome developed in 3.4% of patients.
Other
symptoms
•Headache
•Sore throat
•Rhinorrhea
•Gastrointestinal
symptoms
PRECAUTIONS TO BE ADOPTED IN DENTISTRY
ü What are aerosols in dentistry ?
Dental
procedures that use low- or high-speed handpieces, lasers, electrosurgery
units, ultrasonic scalers, air polishers, prophy angles, hand instruments or
air/water syringes can create bioaerosols and spatter. Ultrasonic
scalers and high-speed handpieces produce more airborne contamination than any
other instrument in dentistry. Inhalation of airborne
particles and aerosols produced during dental procedures may cause adverse
respiratory health effects and bidirectional disease transmission.
Aerosols are differentiated based on
particle size: spatter (> 50 µm), droplet (≤ 50 µm), and droplet nuclei (≤
10 µm). In dental settings, 90% of the aerosols produced
are extremely small (< 5 µm). Spatter, being the larger
particle, will fall until it contacts other objects (e.g., floor, countertop,
sink, bracket, table, computer, patient or operator). Droplets
remain suspended in the air until they evaporate, leaving droplet nuclei that
contain bacteria related to respiratory infections. Droplet
nuclei can contaminate surfaces in a range of three feet and may remain
airborne for 30 minutes to two hours If inhaled,
the droplet nuclei can penetrate deep into the respiratory system.
Furthermore, the susceptibility of developing an infection is influenced by
virulence, dose and pathogenicity of the microorganisms, along with the host’s
immune response.
ü What measures
do we take to protect ourselves from COVID 19?
The
risks of dental aerosols can be reduced with
Ø
The use of high-velocity air evacuation
Ø
Preprocedural antimicrobial mouthrinses, flushing
waterlines at the beginning of the workday and between each patient,
Ø
Wearing personal protective equipment (PPE)
Ø
Using air purifications systems.
These recommendations are published by the CDC as Summary of Infection Prevention Practices
in Dental Settings: Basic Expectations for Safe Care.
High velocity air evacuation
The high-volume evacuator’s (HVE)
large diameter (> 8 mm) allows for removal of high volumes of air in a short
time, which reduces the amount of bioaerosols by up to 90%.9,1
Preprocedural
antimicrobial mouthrinses
Alcohol
Ethyl alcohol, at concentrations
of 60%–80%, is a potent virucidal agent inactivating all of the lipophilic
viruses (e.g., herpes, vaccinia, and influenza virus) and many hydrophilic
viruses (e.g., adenovirus, enterovirus, rhinovirus, and rotaviruses but not
hepatitis A virus (HAV) or poliovirus)
Hydrogen
peroxide
Hydrogen
peroxide is active against a wide range of microorganisms, including bacteria,
yeasts, fungi, viruses, and spores. A 0.5% accelerated hydrogen peroxide
demonstrated bactericidal and virucidal activity in 1 minute and
mycobactericidal and fungicidal activity in 5 minutes.
Bactericidal effectiveness and stability of hydrogen peroxide in urine has been
demonstrated against a variety of health-care–associated pathogens; organisms
with high cellular catalase activity (e.g., S. aureus, S.
marcescens, and Proteus mirabilis) required 30–60 minutes of
exposure to 0.6% hydrogen peroxide for a 108 reduction in cell
counts, whereas organisms with lower catalase activity (e.g., E. coli,
Streptococcus species, and Pseudomonas species) required only
15 minutes’ exposure.
Commercially
available 3% hydrogen peroxide is a stable and effective disinfectant when used
on inanimate surfaces. It has been used in concentrations from 3% to 6% for
disinfecting soft contact lenses (e.g., 3% for 2–3 hrs) , tonometer biprisms ,
ventilator, fabrics, and endoscope. Hydrogen peroxide was effective in
spot-disinfecting fabrics in patients’ rooms
Idophors
Iodine can penetrate the cell
wall of microorganisms quickly, and the lethal effects are believed to result
from disruption of protein and nucleic acid structure and synthesis.
Published reports on the in vitro antimicrobial efficacy of iodophors demonstrate
that iodophors are bactericidal, mycobactericidal, and virucidal but can
require prolonged contact times to kill certain fungi and bacterial spores.
PPE – Personal
Protective Equipment
Standard precautions, as outlined by the
CDC, involve the use of PPE.
Ø Primary
PPE includes donning properly fitting gloves and surgical masks, protective
eyewear with solid side shields or face shield, and protective
clothing/disposable gowns.
Ø This
equipment should be worn whenever there is a potential to encounter spray or
spatter during patient care, and while disinfecting the treatment area (as
noted, bioaerosols remain suspended for 30 minutes to two hours posttreatment).
Ø Masks
and gloves should be changed between patients; moreover, all PPE should be
changed if torn, wet or visibly soiled.
Ø If
providing care for patients with a known infectious disease, the National
Institute for Occupational Safety and Health (NIOSH) requires the wearing of a
NIOSH-certified particulate-filter respirator. To reduce disease transmission,
all PPE must be removed prior to exiting the treatment area.
How to tackle patients in a clinical Setting during
COVID-19 breakout?
ü Telephonic
consulation : This will help the clinician to form a provisional diagnosis
based on history given by the patient.
ü Patient
can be segregated into two categories : Aerosol producing procedures & Non- aerosol producing procedures.
ü Appoint
the patient. Keep the aersol producing procedure in the end of the day.
ü Create
a digital COVID history form, asking patient about any history with the
disease, or close contact with any relative who had an exposure. Save this data
methodically.
ü Instruct
the patient to not get an accompanying person, unless necessary.
ü Tell
the patient to show his AAROGYA SETU APP when they visit the clinic.
ü Keep
a pulse oximeter in the waiting room, to
check the vitals of the patients before commencing the procedure. Any patient
with high temperature, low oxygen saturation should be deferred from the
treatment.
ü Take
an informed consent and digitalise the information or data.
Post COVID era in
dentistry is going to be tough and testing. We are more prone to viral load
because of close proximity to the patients. Prevention is the only cure in sucb
a health emergency.
BIBLIOGRAPHY
SOURCES
AND ARTICLES :
1.
Transmission Precautions
for Dental Aerosols
Understanding the risk posed by aerosols will help
minimize the possibility of infection transmission during dental
procedures.
By
Very well amalgamated piece of information.
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